Book

Proton Therapy Physics

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Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature.

After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy.

The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization.

Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

Table of content:

Proton Therapy: History and Rationale, Harald Paganetti

Physics of Proton Interactions in Matter, Bernard Gottschalk

Proton Accelerators, Marco Schippers

Characteristics of Clinical Proton Beams, Hsiao-Ming Lu and Jacob Flanz

Beam Delivery Using Passive Scattering, Roelf Slopsema

Particle Beam Scanning, Jacob Flanz

Dosimetry, Hugo Palmans

Quality Assurance and Commissioning, Zuofeng Li, Roelf Slopsema, Stella Flampouri, and Daniel K. Yeung

Monte Carlo Simulations, Harald Paganetti

Physics of Treatment Planning for Single-Field Uniform Dose, Martijn Engelsman

Physics of Treatment Planning Using Scanned Beams, Antony Lomax

Dose Calculation Algorithms, Benjamin Clasie, Harald Paganetti, and Hanne M. Kooy

Precision and Uncertainties in Proton Therapy for Nonmoving Targets, Jatinder R. Palta and Daniel K. Yeung

Precision and Uncertainties in Proton Therapy for Moving Targets, Martijn Engelsman and Christoph Bert

Treatment-Planning Optimization, Alexei V. Trofimov, Jan H. Unkelbach, and David Craft

In Vivo Dose Verification, Katia Parodi

Basic Aspects of Shielding, Nisy Elizabeth Ipe

Late Effects from Scattered and Secondary Radiation, Harald Paganetti

The Physics of Proton Biology, Harald Paganetti

Fully Exploiting the Benefits of Protons: Using Risk Models for Normal Tissue Complications in Treatment Optimization, Peter van Luijk and Marco Schippers

Index

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

615.842 PAG p

Penerbit

Boca Raton : CRC Press., 2012

Deskripsi Fisik

xx, 684 p. : illus. ; 23 cm

Bahasa

English

ISBN/ISSN

9781439836446

Klasifikasi

615.842

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

Radiology
1. Paganetti, Harald
II. Series: Series in medical physics and biomedic
Oncology
2. Medical physics
1. Proton beams--Therapeutic use
3. Cancer radiotherapy

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Pernyataan Tanggungjawab

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